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The introduction of sildenafil citrate (Viagra), a drug that acts as a selective inhibitor of cGMP-specific phosphodiesterase sort 5 (PDE5), which ends up in smooth muscle leisure generic viagra in us judpharmacy, vasodilatation, and enhanced penile erection, has been a serious advancement within the therapy of erectile dysfunction.
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Pooled data from fastened- and flexible-dose research point out that sildenafil (50 or one hundred mg) has no impact on sexual need (i.e., rates of attempted intercourse, which averaged about 2 per week), however pfizer manufacturer coupons for viagra the charge of success elevated to a median of 1.3 events per patient per week from 0.4 occasions per week with placebo.